Inner Retinal Mechanisms Engaged by Retinal Electrical Stimulation
نویسندگان
چکیده
منابع مشابه
Inner retinal mechanisms engaged by retinal electrical stimulation.
PURPOSE Retinal prosthetic devices are being developed to bypass degenerated retinal photoreceptors by directly activating retinal neurons with electrical stimulation. However, little is known about retinal activity during such stimulation. METHODS Whole cell patch-clamp recordings were obtained from ganglion and bipolar cells in the salamander retinal slice preparation. A stimulating electro...
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Previous studies have shown that electrical stimulation (ES) increases blood flow, but the exact mechanisms are not clear. The present study was designed to clarify some of the underlying mechanisms involved in this phenomenon. White adult rabbits Lt.-6 months old were used. Animals were anesthetized by sodium pentobarbital (40 mg/kg, IV) and skin blood flow in the thoracic back was recorde...
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Electrical stimulation of the retina following photoreceptor degeneration in diseases such as retinitis pigmentosa and age-related macular degeneration has become a promising therapeutic strategy for the restoration of vision. Many retinal neurons remain functional following photoreceptor degeneration; however, the responses of the different classes of cells to electrical stimuli have not been ...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2006
ISSN: 1552-5783
DOI: 10.1167/iovs.05-1093